ANTHOCRAN® PHYTOSOME®, RELISSA<sup>TM</sup>, MERIVA® AND...
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ANTHOCRAN® PHYTOSOME®, RELISSATM, MERIVA® AND BERBEVIS®: THE FABULOUS FOUR BY INDENA @ VITAFOODS 2022

Pharma Tech Outlook | Tuesday, May 10, 2022

Milan,– Indena is attending the Vitafoods 2022 as a protagonist, both during virtual days, from May the 2nd to 13th, and during the in-presence days of the show, from 10th to 12th May. At the Palexpo of Geneva, Indena will welcome its clients and stakeholders at the Booth 84 to share all the news about its products and services.

“We’re happy to join Vitafoods 2022 with some exciting news, starting from the products we’re going to present as the most recent results of the company’s commitment to performance, innovation and quality in nutraceuticals, for the benefit of human wellbeing – says Francesca de Rensis, Marketing Director at Indena SpA -. Anthocran® Phytosome®, RelissaTM, Meriva® and Berbevis®. Each of these products represents a natural help for some of the most urgent and current health conditions related to today’s lifestyle. Moreover, at Vitafoods we’ll bring Indena’s news about our latest corporate activities, such as sustainability, ingredients personalization and clinical evidence. Together with our experts, we’re sure we’ll have a great opportunity to share with our guests knowledge, ideas, updates about the nutraceutical most important trends and innovations”.

ANTHOCRAN® PHYTOSOME®: THE STRENGTH OF CRANBERRY TO SUPPORT URINARY TRACT HEALTH

Anthocran® Phytosome® is Indena’s cranberry extract, a new health-food ingredient based on Phytosome® formulation proprietary technology, able to enhance and optimize the delivery of the extract where the effects are needed. Anthocran® Phytosome® boasts a unique phytochemical characterization, which makes it the highest quality cranberry extract on the market. In fact, it is standardized in proanthocyanidins (PACs: 6.0-9.0% UV-visible spectrophotometric contents - DMAC method) and contains the full polyphenols profile of natural cranberry, including flavonols, anthocyanins and phenolic acids.

Some recent studies have been carried out by Indena to verify that the complex mixture of proanthocyanidins (PACs), flavonols and phenolic acids contained in Indena’s cranberry extract seems to level biofilm formation.The effectiveness and the safety of Indena’s cranberry extract, includes a pilot registry study1 which investigated the effects of the oral supplementation of Anthocran® Phytosome® for the support of urinary tract health. The clinical evidence shows that Indena’s cranberry extract is a valid supplementation for subjects wishing to keep their UT healthy, with a good tolerability profile.

RELISSATM: SLEEP WELL AND LIVE BETTER, WITH LEMON BALM PHOSPHOLIPIDS

RelissaTM is a health-food ingredient based on the formulation of lemon balm extract from Melissa officinalis with phospholipids, to optimize dispersion in gastrointestinal fluids and biological performances.

More than 50 compounds have been identified in lemon balm plant (including volatiles), but the major active compound is considered to be rosmarinic acid, an hydroxycinnamic acid derivative shown to have multiple properties, among which are calming and anxiolytic effect. Indeed, lemon balm is traditionally known for its effectiveness against tenseness, restlessness and irritability.

Thanks to Melissa officinalis’ well known calming and mood-relaxing effect and to its effectiveness in inducing sleep and improving the sleep duration, RelissaTM, Indena’s Melissa phospholipids, is nowadays a natural important help to face and manage stressing lifestyle. RelissaTM is the result of Indena 100-year experience in botanicals and attention to the ingredient source. In fact, for RelissaTM are chosen the best Melissa officinalis extracts (European origin), with an eye to the environmental footprint and sustainability.

MERIVA®: A NATURAL AND SAFE HELP FOR BODY DETOX

Meriva®, Indena’s curcumin Phytosome®, is the real life guardian, as it continues to reveal new areas of efficacy for human wellbeing. In fact, new clinical evidence shows that Meriva® is an effective oxidative stress modulator, also in the support of kidney detoxing and filtering functions.

Meriva® is the most studied curcumin bioavailable formulation on the market, documented with over 35 clinical studies involving more than 2000 subjects. Its efficacy is demonstrated in many different health conditions, in particular in the areas of cardiovascular, intestinal and ocular health, nutrition in sports, joint health, healthy blood levels, supportive care and today also renal ageing. It is a natural solutions for conditions where response on oxidative stress is involved, including also kidney discomforts.

BERBEVIS®: KEEP YOUR METABOLISM BALANCED, NATURALLY

Berberine is a quaternary ammonium salt (contained in species of the Berberis genus, among which the most important is Berberis Aristata DC) derived from isoquinoline alkaloid and it is supported by reliable scientific literature proving its health benefits in multifactorial conditions. Indena’s Berbevis® is a new and innovative Phytosome® composition applied to Berberis aristata to face the issue of berberine poor bioavailability and to optimize the extract’s health benefits. Clinical evidence shows that Berbevis® is a potent, natural health-food ingredient that might help blood sugar control in a plethora of multifactorial challenges, which represent one of our time’s main global health targets.

MEET THE EXPERTS OF INDENA AT VITAFOODS, TO GO DEEPER IN THE NEWS ON THE WORLD OF BOTANICALS

Vitafoods will be the occasion to meet in person some of the Indena’s authoritative experts, like prof. Attilio Giacosa, prof. Giovanni Appendino and dr. Serena Tongiani, following their presentations about new products and some important topics related to the nutraceutical world.

• The latest ally for GI tract disorders: Curcuma longa and Boswellia serrata extracts “smart” formulation, by Prof. Attilio Giacosa, Scientific Advisor, Indena New Ingredients Theatre, May 10th, 14:00 pm

• Adult health and active life style: the botanical ingredients that can make a difference, by Prof. Giovanni Appendino, Scientific Advisor, Indena Life Stages Theatre, May 11th, 12:30 pm

• Anthocran® Phytosome®: a new and more bioavailable cranberry extract, by Dr. Serena Tongiani, Chief Product Officer, Indena New Ingredients Theatre, May 11th, 16:00 pm.

Indena's presentations may beattendedin person Vitafoods or online on https://www.vitafoods.eu.com/en/visit/agenda.html.

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