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Dyno Therapeutics raises $9M from its Seed Funding round right after breaking its stealth mode
Fremont, CA: Dyno Therapeutics, a Cambridge-based biotechnology company, raised $9m in not previously announced seed financing round. The company Dyno, spun out of the lab of Prof. George Church of Harvard, specializes in applying artificial intelligence (AI) to gene therapy. The seed funding round was co-led by Polaris Partners and CRV.
Led by Eric Kelsic, Ph.D., CEO, and Co-founder, Dyno broke its stealth mode by launching its proprietary platform, CapsidMap. The platform utilizes proprietary AI technology to discover and design the novel AAV capsids, the cell-targeting protein shell of viral vectors. Dyno’s CapsidMap systematically produces and analyzes millions of new AAV variants at scale, accelerating the recognition of improved AAV vectors. It uses advanced machine learning search algorithms, in combination with high-throughput experiments that generates massive quantities of in vivo data, to kickstart the creation of superior synthetic AAV capsids.
Dyno’s R&D and collaborations with biopharmaceutical companies host active programs related to novel gene therapy vectors for ophthalmic, muscle, central nervous system (CNS), and liver diseases. The CapsmidMap platform develops based on specific intellectual property created in the lab of George Church, Ph.D., who is Robert Winthrop Professor of Genetics at Harvard Medical School (HMS) and a Core Faculty member at Harvard’s Wyss Institute for Biologically Inspired Engineering. Dyno has a specific option to take part in a license agreement with Harvard University, especially for this technology. Church is also the Chairman of the company’s Scientific Advisory Board and a co-founder of Dyno.
Alan Crane, a co-founder of Dyno and Entrepreneur Partner at Polaris Partners, and Dylan Morris, General Partner at CRV, has joined Dyno’s board of directors, along with Alan Crane assuming the role of Dyno’s Executive Chairman.
Additionally, the founders of Dyno include Sam Sinai, Ph.D., Lead Machine Learning Scientist, Adrian Veres, Ph.D., Scientific Advisor, and Tomas Bjorklund, Ph.D., a scientific advisor of Dyno who is Associate Professor at Lund University and a leader in AAV capsid engineering.