Biocare Medical
Handy Antibody Library and IVD Grade Markers

Immunohistochemistry (IHC) and in situ hybridization (ISH) have widely been used to diagnose and research cancer due to convenience and reliability. This has resulted in the development and study of specific immunotherapy markers in recent times and has shown the potential to impact how cancer will be treated in the future. To successfully carry out IHC and ISH to differentiate between different types of cancers, these antibody markers need to be efficacious enough to transition from research into clinical utility within the laboratories. Aiding laboratories in simplifying the pursuit of quality antibodies is Pacheco, California-based Biocare Medical. The company has established itself as the trusted source of such quality and IHC optimized antibodies in the immunotherapy space.

Biocare offers a vast portfolio of reagents, instrumentation, and support for immunohistochemistry and in situ hybridization clients and is currently focused on research customers invested in immunotherapy applications. “We have expanded our portfolio of reagent offerings rapidly to address the demand for immunotherapy markers such as TIGIT, LaG-3 and GITR, among others,” informs Chris Gildea, Chief Commercial Officer, Biocare Medical. In addition, the company caters to two specific customer sets with their instrumentation offerings, intelliPATH FLX serving both research & clinical customers, while Oncore Pro serving clinical customers.

The ONCORE Pro platform is designed for rapid clinical IHC, automated FISH and HPV diagnostic applications. The system offers 36 slide automated slide staining system that streamlines the staining process by utilizing advanced online antigen retrieval technology, pre-optimized reagents, and ready-to-use antibodies to enhance laboratory workflow, increase laboratory efficiency, and reduce hands-on processing time. In addition, the platform is designed for speed, low volume dispense volumes, minimal waste, and a small footprint. For technicians and researchers looking for more flexibility in their approach, Biocare offers the intelliPATH FLX semi-automated platform which offers an open-source software system geared towards both clinical and research applications.

We have expanded our portfolio of reagent offerings rapidly to address the demand for immunotherapy markers such as TIGIT, LaG-3 and GITR, among others

The platform can handle large slide batches, discrete small batches, and a combination of batch and STAT slides. Developed using a suite of high-performance technologies that includes simultaneous Multiplex IHC capability, ‘no touch’ liquid level sensing, and simultaneous X and Y movement, the intelliPATH FLX can provide a rapid turnaround time with an innovative slide staining system and optimized reagents.

Both instrument offerings from Biocare Medical offer a broad library of antibodies and accessory devices for the IHC and ISH applications. “We have over 300 antibodies in our antibody portfolio and over 20 of them are dedicated specifically to the immunotherapy space,” says John Steel, Director of Marketing and E-commerce.

In addition, Biocare has developed an antigen retrieval device called Decloaking Chamber that is designed for heat-induced epitope retrieval and ease of use. Using the chamber, laboratories can optimize and standardize antibody staining procedures and transfer run data, including temperature, pressure, and time, through a USB device to their computer.

To make these offerings easily accessible, the Biocare team has developed an e-commerce platform geared around customers' needs for reagents and instruments. The company is focused on ensuring that their client’s requests are met with appropriate response and delivered with a standard offering for all customers. Searching for the antibody you need and quick ordering is made easy on Biocare’s user friendly website.

The Biocare team is dedicated to providing clients a reliable, flexible, robust and relevant offering alongside 24/7 support across the IHC, ISH, FISH and HPV diagnostic spectrum.