Clario
Enhancing Evidence Through Modern Trial Solutions

Clario is a clinical trial data management company that generates the richest clinical evidence for pharmaceutical, biotech, and medical device partners. By combining deep scientific expertise with a global reach, Clario has supported over 26,000 trials over its 50-year history and contributed to over 700 FDA and EMA regulatory approvals—approximately 60 percent of all FDA approvals between 2012 and 2023.

At the core of Clario’s offerings is a broad range of endpoint technology services for clinical trial management, including regulatory consultation and statistical analysis. Its solutions assess drug efficacy, safety, and patient quality of life through high-quality digital endpoint solutions and operational excellence. These include electronic Clinical Outcome Assessment (eCOA), cardiac safety, medical imaging, precision motion, and respiratory endpoints.

Clario is committed to transforming lives by unlocking better evidence through their scientific expertise and technology. The company delivers the richest clinical evidence across all trial models through its broadest endpoint technology platform. The platform enhances clinical trial efficacy, ensures patient safety, and improves participants’ overall quality of life. Its technology platform includes services across cardiac safety, eCOA (electronic clinical outcome assessment), medical imaging, precision motion, and respiratory. The eCOA solutions improve patient accessibility by enabling sponsors to deliver tools for at-home use and supporting trials in offline, virtual, and hybrid formats.

“Scientific expertise is embedded within our team of clinical trial management professionals, who ensure that therapeutic area knowledge and endpoint science inform every aspect of their evidence generation technologies,” says Chris Fikry, M.D., President and CEO of Clario.

With a presence in over 100 countries and translations in more than 100 languages, Clario seamlessly executes clinical trials on a global scale. Its deep regulatory and operational expertise enables efficient navigation of international trial complexities, ensuring compliance at every stage. Backed by extensive global regulatory experience, Clario enhances the reliability and precision of clinical evidence across its technology portfolio, supporting diverse trial designs, including site-based, hybrid, and decentralized models.

Scientific expertise is embedded within our team of clinical trial management professionals, who ensure that therapeutic area knowledge and endpoint science inform every aspect of their evidence generation technologies

In addition to supporting traditional trials, Clario plays a pivotal role in decentralized trials, offering sponsors and sites greater flexibility while empowering patient choice and promoting health equity. By providing the necessary technology, expertise, and infrastructure for decentralized, hybrid, and site-based trials, Clario improves diversity and inclusivity in clinical research.

The company is also committed to simplifying the clinical trial process for sponsors, sites, and CROs by seamlessly integrating endpoint technologies with scientific expertise and global reach. Its platform provides round-the-clock partner and patient support and integrated training and instructions, ensuring a smooth and efficient experience for all stakeholders. By staying ahead of emerging clinical research trends and proactively addressing trial planning and database security challenges, Clario continues to drive innovation in clinical trial management.

As a testament to its impact, the firm played a crucial role in Eisai’s Alzheimer’s disease treatment, LEQEMBI. Clario’s scientific expertise and standardized data collection supported multiple study protocols and phases, ensuring the comprehensive evidence needed to evaluate safety and effectiveness. It oversaw the examination and analysis of over 35,000 MRI and amyloid PET time points and managed cardiac safety data collection across more than 250 sites in 14 countries—demonstrating their vital contribution to the success of novel medicines.

With a strong legacy in drug approvals and a forwardlooking approach to decentralized trials and patient-centric solutions, Clario continues to shape the future of clinical research. By streamlining processes, ensuring data integrity, and expanding access to trials, the company accelerates the development of life-changing therapies and improves patient outcomes worldwide.