Entera Health
Natural Immune Enhancement Products

There are multiple ways for businesses in the immune health supplements market to provide value to both patients and physicians. One is a traditional route with a targeted approach to immunotherapy through the regulation of Cytokines or TNF-alpha drugs. However, such products not only cause adverse side effects but they also fail to positively impact the underlying problem leading to immune dysregulation. The alternative approach, however, is for companies to develop effective natural products while accounting for the safety of consumers of all different ages. “We focus on patient safety, but at the same time the product has to work, it must be clinically efficacious” begins Dr. Chris Detzel, PhD., General Manager at Entera Health.

Entera Health manufactures ingredients used in both supplements and medical foods. These ingredients provide safe and effective natural solutions for complex immune challenges. “We are not a traditional pharmaceutical company as we look for natural solutions to treat chronic conditions,” states Detzel. The company provides products that are rich in immunoglobulin content with a primary focus on supporting the gastrointestinal immune system.

Entera Health specializes in GI immune support and, through its partnerships with other pharma businesses, develops efficacious products that are science-backed through research. “We look to solve challenges where inflammation within the body is out of balance,” adds Detzel. Naturally, the human gut produces about five grams of immunoglobulin per day which is extremely critical in both signalling and neutralization of inflammatory components within the GI tract.

Entera Health’s products provide an exogenous source of immunoglobulin that helps support the natural production of immunoglobulin by the gastrointestinal immune system. “Our product neutralizes the inflammatory antigens that result from the natural breakdown products of the gut microbiome,” adds Detzel.

Gut barrier damage and the resultant inflammation often work together in an accelerating cyclical cascade that can exacerbate GI inflammation and contribute to serious GI diseases. In such cases, the functionality of the GI tract is hindered and can lead to diarrhea, bloating, and other symptoms of GI dysfunction. Entera Health’s products deliver immunoglobulin into the GI tract to help manage nflammation. When the exogenous antibodies in Entera Health’s products enter the GI system, they bind inflammatory antigens in the gut and neutralize their negative effects on the gut barrier and inflammation. Therefore, the gut has a chance to reset and heal and eventually restore normal gut function. This is the value proposition Entera Health imparts to its consumers.

Currently, Entera Health is focused on development of products that affect the mucosal immune system, with the idea that the mucosal sites throughout the body are interconnected (the respiratory, gastrointestinal, and urogenital systems) and can be impacted through orally administered health products with the potential to act locally in the gut and on other mucosal sites throughout the body. The firm is also studying the effect of consuming oral immunoglobulins on the microbiome and its link to physiological effects throughout the body.

Moreover, Entera Health is conducting preclinical research in the area of the gut-brain axis and a clinical program in Covid-19 to better understand the link between different systems and explore opportunities for new products. On the geographical front, the company has already established itself in the US and is looking to expand its footprint in Southeast Asia, Middle East, and Europe. As consumers continue to push for natural solutions Entera Health is well positioned to work with healthcare companies to supply natural products and meet these expectations through their ImmunoLin and EnteraGam product offerings.