The Role of Laboratory Automation in the Pharma Industry

Pharma Tech Outlook: Pharma Tech Magazine

The Role of Laboratory Automation in the Pharma Industry

By Pharma Tech Outlook | Wednesday, December 16, 2020

As the power of automation rises, so will the ability of the modern chemist. More samples can be tested in the laboratory setting with accuracy and granularity for an increased understanding of the chemical process.

FREMONT, CA: Laboratory automation is being increasingly applied in the pharmaceutical industry to help meet the needs of rising productivity, decreasing drug development time, and mitigating costs. Automation can be called a system that can perform a variable but programmed series of physical manipulations, including moving objects, sample identification, weighing, extraction, filtration, and dilution. Using this powerful automation tool, the chemist can run several experiments under different conditions to fully understand the reaction dynamics. Here is more to smart labs soltuion companies

Design of experiment (DoE) techniques utilize automation alongside sophisticated modeling and applied statistics, enabling informed decisions to be made in connection with which chemical reactions can be progressed to the next level of process development. Total laboratory automation is now possible for individual clinical laboratories. Using TLA, all input processes like sample preparation and barcoding are all automated right through to the output processes like report generating and data analysis. This automation level has shown drastic improvement in turnaround times for samples, resulting in cost savings and the increased accuracy of results.

Any process must be developed with safety as a vital priority. The controlling system and automation must also reflect this. Automatic shutdown procedures offer a desirable level of safety. These can be user-defined and powered by the present operating conditions of the system. The feed for a reaction could be set to automatically switch off if the system temperature increased above a defined limit, thus enabling the temperature control system to regain safe operational conditions. Additional protection levels can be set up so that if the first shutdown procedure was insufficient and the temperature continued to increase, emergency cooling would activate. If the temperature rises further, a quenching agent could be activated.

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With these automatic safety systems in place, manufacturing chemists can run a process with fewer manual communications. They can also leave the system unattended, knowing there are appropriate protocols in place to guard the system in a worst-case scenario.

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