Nexcelom Bioscience
Trailblazing New Standards in Cell Counting and Analysis

For over 150 years, cell counting has been a quintessential tool for diagnostic analysis. However, even until 15 years ago, most scientists in life science laboratories put a hemocytometer glass chip under a microscope, and manually look at the cells through the microscope and count for 10 to 15 minutes to get the numbers. But ever since Massachusetts-based Nexcelom Bioscience stepped into the picture as the pioneers reshaping the future of cell counting and analysis through innovation and expertise in image cytometry, it has put an end to the strenuous and time-consuming process of manually counting cells and analyzing them.

With groundbreaking technologies like CRISPR, scientists are now delving deep into the cells' complexity and are analyzing them in a very systematic single cell-based approach for adjusting and manipulating the genetic makeup of the cells. And effective cell counting is one of those crucial steps that will help them ensure cell quality to create sophisticated cell models like 3d organoids and spheroids. At the same time, scientists can't afford to spend an excess of hours and effort for minutely counting and analyzing cells to advance their research projects.

To address this widespread concern in the life sciences industry, Nexcelom Bioscience has pioneered image cytometry for effectively counting cells. Owing to thecost-efficiency and high throughput of image cytometry, Nexcelom Bioscience delivers top-notch products that range from advanced image cytometry workstations (Celigo) to high-throughput automated cell counters (Cellaca MX) that counts a large numbers of samples in just a few minutes. The devices are widely adopted by thousands of research laboratories across academic institutes as well as numerous pharmaceutical and biotech companies. "We deliver high-quality, reliable products using image cytometry technology, addressing a wide variety of critical cell counting and measurement applications," says Peter Y. Li, CEO of Nexcelom Bioscience.

We deliver high-quality, reliable products using image cytometry technology, addressing a wide variety of critical cell counting and measurement applications

The company's flagship product, Cellaca MX High Throughput Automated Cell Counter, can run up to 24 samples in less than three minutes. Researchers don't need to reload individual slides anymore or wait for small-batch counters to finish counting. Additionally, multiple fluorescent filter options enable scientists to perform cell-based assays in minutes while supporting robotic integration with optional API. "Scientists need measure cells quickly to attend a huge number of samples coming through. This is exactly what we are addressing through Cellaca," says Li.

Yet another noteworthy offering in Nexcelom Bioscience's portfolio, Celigo, is a plate-based benchtop fluorescent imaging system designed for live-cell analysis and cell sample characterization. With an intuitive software interface and optional integration into automation platforms, Celigo furthers a laboratory's cell-based assay capabilities and proves to be valuable at manysteps during the discovery and development workflow for novel drug modalities.

"Our organisation doesn't just look at cell counting as a routine task as people have done in the past. For creating accurate and reliable cell counting methods and solutions, we have been building a scientific foundation through engaging collaborations with our customers," adds Li. Always staying true to that belief, the company works collaboratively with the scientists and academicians whilelaunchingnew products, and Nexcelom scientists actively collaborate and publish scientific papers along with their clients in peer river review journals to advance scientific developments in cell counting and cell analysis.

Building on its strength of delivering fit-for-purpose cell counting solutions for a wide variety of cell types from different cell samples, Nexcelom Bioscience has recently launched a new software platform that runs both Cellometer and Cellaca instruments. "Now scientists can choose Cellaca or Cellometer cell counters depending on their workflow needs, while knowing that the instruments are built on a harmonized platform designed for their entire process," concludes Li.